CBSE Class 12 Biology sample paper 2024-25: question 18(B)
From the official CBSE sample question paper for 2024-25, section B, question 18(B), for 2 marks. Try it first; the hints and our step-by-step solution are below.
Q18(B) · 2 marks · Very short answerCompetency-basedMolecular Basis of Inheritance
Given below is a schematic representation of a mRNA strand
5' AGGAGGUAUGAUCUCGUAAAAUAAA 3'
(i) In the above sequence identify the translational unit in mRNA.
(ii) Where are UTRs found and what is their significance?
Figure in the paper: A line labelled mRNA from 5' to 3' with the base sequence AGGAGGUAUGAUCUCGUAAAAUAAA written below. See it in the official paper.
Source: official sample paper from cbseacademic.nic.in (PDF). See it in the full Sample paper 2024-25.
Hints
Open one hint at a time and try again before the next.
Hint 1
Look for the start codon AUG in the sequence.
Hint 2
Read in triplets from AUG until you reach a stop codon (UAA, UAG or UGA).
Hint 3
The bases left over on either side are the UTRs.
Step-by-step solution
Each step shows the marks it earns, as an examiner would award them. Checked by an independent re-solve from the question paper.
- 1 mark
(i) The translational unit is the stretch from the start codon AUG to the stop codon UAA, which codes for a polypeptide:
5′ AGGAGGU AUG AUC UCG UAA AAUAAA 3′
Translational unit = AUG AUC UCG UAA.
- ½ mark
(ii) UTRs (untranslated regions) are found at the 5′ end, before the start codon (AGGAGGU here), and at the 3′ end, after the stop codon (AAUAAA here).
- ½ mark
(ii) Significance: UTRs are not translated, but they are required for efficient translation of the mRNA.
Answer: (i) AUG AUC UCG UAA; (ii) UTRs lie at the 5′ end before AUG and at the 3′ end after the stop codon; they are needed for efficient translation.
Where the marks are
- Identifies the translational unit AUG AUC UCG UAA, flanked by start and stop codons (1 mark)
- States the location of UTRs at the 5′ end (before start codon) and 3′ end (after stop codon) (0.5 mark)
- States that UTRs are required for efficient translation (0.5 mark)
Revise the chapter
- Chapter: Molecular Basis of Inheritance (notes, formulas, where marks are lost and every past question)
- Topic: Genetic Code and Translation
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