Neural Control and Coordination Class 11 Biology: Neuron, Nerve Impulse, Synapse and Brain
Updated 15 October 2026 · Fact-checked
Neural Control and Coordination is Chapter 18 of CBSE Class 11 Biology, in Unit V, Human Physiology. It covers the neural system of animals, the human central, peripheral and visceral nervous systems, the structure and types of neurons, generation and conduction of nerve impulses, synaptic transmission, and the forebrain, midbrain and hindbrain.
What Neural Control and Coordination is about
Organs and organ systems must work together to keep the body stable (homeostasis). Coordination is the process by which two or more organs interact and complement each other's functions. For example, during exercise, muscles need more energy and O₂, so breathing rate, heart rate and blood flow all increase together; when exercise stops, they return to normal.
Two systems coordinate the body: the neural system (fast, point-to-point) and the endocrine system (chemical, slower). This chapter covers the neural system.
Main ideas:
1. Neural systems differ across animals: a network of neurons in *Hydra*; a brain with ganglia and neural tissues in insects; the most developed system in vertebrates.
2. Human neural system: CNS (brain and spinal cord: information processing and control) and PNS (all nerves; afferent and efferent fibres), divided into somatic and autonomic (sympathetic and parasympathetic) parts. The visceral nervous system links the CNS with internal organs.
3. Neuron: cell body, dendrites, axon; multipolar, bipolar or unipolar; myelinated or non-myelinated.
4. Nerve impulse: a resting axon is polarised (inside negative); a stimulus lets Na⁺ rush in, depolarising it (action potential), and the wave travels along the axon.
5. Synapse: electrical (direct current flow, rare, fast) or chemical (neurotransmitters cross a cleft).
6. Brain: forebrain (cerebrum, thalamus, hypothalamus, limbic system), midbrain (corpora quadrigemina), hindbrain (pons, cerebellum, medulla).
Flow chart of impulse transmission:
stimulus → Na⁺ enters → action potential at that point → local currents depolarise the next point → impulse travels to axon terminal → Ca²⁺-triggered release of neurotransmitter → binds receptors on next neuron → new impulse (or inhibition).
Not in the 2026-27 syllabus: reflex action and reflex arc; the eye and the ear (sensory reception).
This chapter is part of Unit V, Human Physiology (18 of 70 theory marks). Expect neuron and brain diagrams, polarisation and depolarisation, synaptic transmission and functions of brain parts.
Weightage: This chapter is part of Unit V, Human Physiology, which carries 18 of the 70 theory marks in the school annual exam together with Breathing and Exchange of Gases, Body Fluids and Circulation, Excretory Products and their Elimination, Locomotion and Movement and Chemical Coordination and Integration.Source: CBSE Biology (044) syllabus 2026-27, Class XI course structure, Unit V Human Physiology
Key concepts
- Neural system and the human neural system
- NCERT section 18.1 Neural System; 18.2 Human Neural System
Neural system: a highly organised network of point-to-point connections that allows quick coordination. Its units are neurons, specialised cells that can detect, receive and transmit different kinds of stimuli.
In animals:
- Lower invertebrates: very simple. In *Hydra* it is a network of neurons.
- Insects: better organised: a brain with a number of ganglia and neural tissues.
- Vertebrates: the most developed neural system.
Human neural system has two parts:
1. Central neural system (CNS): brain and spinal cord. It is the site of information processing and control.
2. Peripheral neural system (PNS): all the nerves of the body linked with the CNS. Nerve fibres are of two types:
- Afferent fibres: carry impulses from tissues/organs to the CNS.
- Efferent fibres: carry regulatory impulses from the CNS to tissues/organs.
The PNS has two divisions:
- Somatic neural system: carries impulses from the CNS to skeletal muscles (voluntary actions).
- Autonomic neural system: carries impulses from the CNS to involuntary organs and smooth muscles. Further divided into the sympathetic and parasympathetic neural systems (which usually have opposite effects, e.g. on heart rate).
Visceral nervous system: the part of the PNS made up of the whole set of nerves, fibres, ganglia and plexuses through which impulses pass from the CNS to the viscera (internal organs) and from the viscera back to the CNS.
Tree diagram:
Neural system → CNS (brain, spinal cord) + PNS → somatic + autonomic (sympathetic, parasympathetic); visceral nervous system links CNS and viscera.Worked example
A student decides to raise her hand to answer a question, while her heart starts beating faster because she is nervous. For each response, name the division of the PNS that carries the command from the CNS and the type of muscle it reaches. What type of fibres carry these commands, and what type would carry information from the heart back to the CNS? (2 marks)
Try it first, then show the solutionSolution
- Raising the hand: somatic neural system to skeletal muscles; faster heartbeat: autonomic neural system (sympathetic division) to the involuntary cardiac muscle. (1)
- Commands from the CNS travel in efferent fibres; information from the heart to the CNS travels in afferent fibres (part of the visceral nervous system). (1)
Answer: Somatic → skeletal muscle; autonomic (sympathetic) → heart; efferent fibres carry commands, afferent fibres carry information back.
- Neuron: structure and types
- NCERT section 18.3 Neuron as Structural and Functional Unit of Neural System
A neuron is a microscopic structure with three main parts:
1. Cell body (cyton): contains cytoplasm with typical cell organelles and certain granular bodies called Nissl's granules.
2. Dendrites: short fibres that branch repeatedly and project out of the cell body; they also contain Nissl's granules and carry impulses towards the cell body.
3. Axon: a long fibre, whose distal end is branched. Each branch ends as a bulb-like synaptic knob, which has synaptic vesicles containing chemicals called neurotransmitters. Axons carry impulses away from the cell body to a synapse or a neuromuscular junction.Types by number of axons and dendrites:
- Multipolar: one axon and two or more dendrites; found in the cerebral cortex.
- Bipolar: one axon and one dendrite; found in the retina of the eye.
- Unipolar: cell body with one axon only; found usually in the embryonic stage.
Types of axons:
- Myelinated: enveloped by Schwann cells, which form a myelin sheath around the axon. The gaps between adjacent myelin sheaths are the nodes of Ranvier. Found in spinal and cranial nerves.
- Non-myelinated (unmyelinated): a Schwann cell surrounds the axon but no myelin layer is wrapped around it. Commonly found in the autonomous and somatic neural systems.
Dendrite vs axon: dendrites are short, many, branched, with Nissl's granules, carrying impulses towards the cell body; the axon is long, usually single, without Nissl's granules, carrying impulses away and ending in synaptic knobs.
Worked example
Name the type of neuron found (a) in the cerebral cortex and (b) in the retina, and give the structural basis of each type. (2 marks)
Try it first, then show the solutionSolution
- (a) Multipolar: one axon and two or more dendrites. (1)
- (b) Bipolar: one axon and one dendrite. (1)
Answer: Multipolar (cortex); bipolar (retina).
- Generation and conduction of a nerve impulse
- NCERT section 18.3.1 Generation and Conduction of Nerve Impulse
Neurons are excitable because their membranes are polarised: different types of ion channels are present on the membrane, and they are selectively permeable to different ions.
Resting state (polarised membrane):
- When a neuron is not conducting an impulse, the axonal membrane is comparatively more permeable to K⁺ and nearly impermeable to Na⁺.
- It is also impermeable to negatively charged proteins present in the axoplasm.
- So the axoplasm has a high concentration of K⁺ and negatively charged proteins and a low concentration of Na⁺; the fluid outside has a low K⁺ and high Na⁺ concentration: a concentration gradient.
- These gradients are maintained by active transport by the sodium-potassium pump, which moves 3 Na⁺ out for every 2 K⁺ in.
- As a result, the outer surface is positively charged and the inner surface negatively charged: the membrane is polarised.
- The electrical potential difference across the resting membrane is the resting potential.
Stimulation (depolarisation and action potential):
1. When a stimulus is applied at a site (say A), the membrane there becomes freely permeable to Na⁺.
2. Na⁺ rushes in, reversing the polarity at A: the outer surface becomes negative and the inner surface positive. The membrane at A is depolarised.
3. This potential difference at A is the action potential, also called a nerve impulse.
4. At the next site (B) just ahead, the membrane is still positive outside and negative inside. A current flows on the inner surface from A to B and on the outer surface from B to A, completing a circuit.
5. So polarity at B is reversed: an action potential is generated at B. The impulse is conducted along the axon, repeating the sequence.
6. The rise in Na⁺ permeability is very short-lived. It is quickly followed by a rise in K⁺ permeability; K⁺ diffuses out, restoring the resting potential at the site, and the fibre is ready for further stimulation.Sequence: resting (polarised) → stimulus → Na⁺ in (depolarisation, action potential) → K⁺ out (repolarisation) → Na⁺-K⁺ pump keeps gradients.
Worked example
Put these events at one point on an axon in the correct order and give the charge on the inner surface after each: (i) K⁺ permeability rises, (ii) a stimulus is applied, (iii) Na⁺ rushes in, (iv) the membrane is at rest, (v) the membrane becomes freely permeable to Na⁺, (vi) the resting potential is restored. (3 marks)
Try it first, then show the solutionSolution
- (iv) at rest: inside negative → (ii) stimulus → (v) membrane freely permeable to Na⁺. (1)
- (iii) Na⁺ rushes in: polarity reverses, inside positive (depolarised; the action potential). (1)
- (i) the short-lived Na⁺ permeability is followed by a rise in K⁺ permeability; K⁺ diffuses out → (vi) inside negative again, ready for the next stimulus. (1)
Answer: iv (−) → ii → v → iii (+, action potential) → i → vi (−).
- Transmission of impulses: synapses
- NCERT section 18.3.2 Transmission of Impulses
An impulse passes from one neuron to another through a junction called a synapse. Two membranes meet here, that of the pre-synaptic neuron (sending) and the post-synaptic neuron (receiving); in some synapses a gap, the synaptic cleft, lies between them.
Electrical synapse:
- The pre- and post-synaptic membranes are very close to each other.
- Electric current can flow directly from one neuron to the next; transmission is very similar to conduction along a single axon.
- Transmission across an electrical synapse is always faster than across a chemical synapse.
- Electrical synapses are rare in our system.
Chemical synapse:
- The membranes are separated by a fluid-filled space, the synaptic cleft.
- Neurotransmitters carry the impulse across.
- Steps:
1. The impulse (action potential) reaches the axon terminal.
2. It stimulates synaptic vesicles to move towards the membrane, fuse with it and release neurotransmitters into the cleft.
3. Neurotransmitters bind to specific receptors on the post-synaptic membrane.
4. Binding opens ion channels, allowing entry of ions that can generate a new potential in the post-synaptic neuron.
5. The new potential may be excitatory or inhibitory.Why one-way? Neurotransmitter is released only from the pre-synaptic knob and receptors are only on the post-synaptic membrane, so impulses at chemical synapses pass in one direction only.
Worked example
Compare electrical and chemical synapses in three ways. (3 marks)
Try it first, then show the solutionSolution
- Gap: membranes very close in electrical; separated by a fluid-filled synaptic cleft in chemical. (1)
- Mechanism: direct current flow in electrical; neurotransmitters released and bound to receptors in chemical. (1)
- Speed and frequency: electrical faster but rare; chemical slower but common, and can be excitatory or inhibitory. (1)
Answer: Close contact/current/fast/rare vs cleft/transmitters/slower/common.
- Central neural system: protection and forebrain
- NCERT section 18.4 Central Neural System (18.4.1 Forebrain)
The brain is the central information processing organ and acts as the command and control system. It controls voluntary movements, balance, functioning of vital involuntary organs (lungs, heart, kidneys), thermoregulation, hunger and thirst, circadian (24-hour) rhythms, activities of several endocrine glands and human behaviour. It is also the site of processing of vision, hearing, speech, memory, intelligence, emotions and thoughts.
Protection: the brain is protected by the skull. Inside the skull it is covered by cranial meninges: an outer dura mater, a very thin middle arachnoid and an inner pia mater, which is in contact with brain tissue.
Three major parts: forebrain, midbrain and hindbrain.
Forebrain: cerebrum, thalamus and hypothalamus.
- Cerebrum: the major part of the brain. A deep cleft divides it into left and right cerebral hemispheres, connected by a tract of nerve fibres, the corpus callosum.
- Cerebral cortex: the layer of cells covering the hemispheres, thrown into prominent folds. It is the grey matter, because neuron cell bodies are concentrated there.
- Contains motor areas, sensory areas and large association areas (neither clearly sensory nor motor), responsible for intersensory associations, memory and communication.
- White matter: the inner part of the hemispheres, formed by tract fibres covered with myelin sheath, giving an opaque white look.
- Thalamus: the cerebrum wraps around it; a major coordinating centre for sensory and motor signalling.
- Hypothalamus: at the base of the thalamus. Has centres controlling body temperature and the urge for eating and drinking. Contains neurosecretory cells that secrete hypothalamic hormones.
- Limbic system (limbic lobe): the inner parts of the hemispheres with deep structures such as the amygdala and hippocampus. Together with the hypothalamus it regulates sexual behaviour, emotional reactions (excitement, pleasure, rage, fear) and motivation.
Worked example
Why is the cerebral cortex called grey matter and the inner part of the cerebrum white matter? Name the structure joining the two hemispheres. (3 marks)
Try it first, then show the solutionSolution
- The cortex is grey because neuron cell bodies are concentrated there. (1)
- The inner part is white because it consists of nerve fibre tracts covered with myelin, which looks opaque white. (1)
- The corpus callosum connects the two cerebral hemispheres. (1)
Answer: Cell bodies (grey) vs myelinated fibres (white); corpus callosum.
- Midbrain, hindbrain and brain stem
- NCERT section 18.4.2 Midbrain; 18.4.3 Hindbrain
Midbrain:
- Located between the thalamus/hypothalamus of the forebrain and the pons of the hindbrain.
- A canal, the cerebral aqueduct, passes through it.
- Its dorsal part is made mainly of four round swellings (lobes) called corpora quadrigemina.
Hindbrain: pons, cerebellum and medulla (medulla oblongata).
- Pons: made of fibre tracts that interconnect different regions of the brain.
- Cerebellum: has a very convoluted (folded) surface, which provides extra space for many more neurons. (It helps maintain posture and balance.)
- Medulla: connected to the spinal cord. Contains centres controlling respiration, cardiovascular reflexes and gastric secretions.
Brain stem: made of the midbrain, pons and medulla oblongata. It connects the brain and the spinal cord.
Quick table in words:
- Forebrain: thinking, sensation, voluntary action (cerebrum); relay (thalamus); temperature, hunger, thirst, hormones (hypothalamus); emotions (limbic system).
- Midbrain: corpora quadrigemina; cerebral aqueduct.
- Hindbrain: links (pons); balance and coordination (cerebellum); breathing, heart and gut reflexes (medulla).
Worked example
Name the part of the brain that (a) contains the centres for breathing and heart reflexes, (b) has four round swellings on its dorsal side, (c) links different regions through fibre tracts, (d) forms the brain stem together with the medulla. (2 marks)
Try it first, then show the solutionSolution
- (a) Medulla oblongata; (b) midbrain (corpora quadrigemina). (1)
- (c) Pons; (d) midbrain and pons. (1)
Answer: Medulla, midbrain, pons, midbrain + pons.
Neural Control and Coordination in real life
Each concept, met in an everyday situation. Read the situation, answer the question in your own words, then compare with the model answer. The one-line hook is what to remember.
Midbrain, hindbrain and brain stem
Suppose a person who has drunk too much alcohol staggers, cannot walk in a straight line and keeps losing balance.
Which part of the brain is most affected, and why does balance fail?
Try it first, then show the solutionSolution
- The cerebellum, in the hindbrain, coordinates movement and maintains posture and balance.
- Its highly folded surface packs in huge numbers of neurons for this coordination.
- Alcohol depresses cerebellar function, so muscle movements are poorly coordinated and the person sways.
Answer: The cerebellum; it coordinates movement and balance.
Memory hook: Cerebellum keeps you balanced.
Generation and conduction of a nerve impulse
Imagine a dentist injects a local anaesthetic before filling a tooth, and you feel nothing from that tooth for an hour, though you can still move your tongue.
Explain how a local anaesthetic can stop pain signals, using the nerve impulse mechanism.
Try it first, then show the solutionSolution
- Pain signals travel as action potentials along sensory nerve fibres from the tooth to the CNS.
- An action potential needs Na⁺ to rush into the axon through Na⁺ channels.
- If the anaesthetic blocks these Na⁺ channels near the tooth, depolarisation cannot occur, so no impulse reaches the brain and no pain is felt.
Answer: Blocking Na⁺ entry stops action potentials in the sensory nerve.
Memory hook: No Na⁺ in, no impulse, no pain.
Central neural system: protection and forebrain
Suppose on a very hot day you feel thirsty and start sweating, and later on a cold night you shiver; both responses seem to happen on their own.
Which part of the brain controls these responses?
Try it first, then show the solutionSolution
- The hypothalamus, at the base of the thalamus in the forebrain, has centres controlling body temperature.
- It also controls the urge to eat and drink, causing thirst.
- It triggers sweating to lose heat and shivering to make heat, keeping body temperature steady.
Answer: The hypothalamus.
Memory hook: Hypothalamus = body's thermostat and thirst centre.
Topics in this chapter
Neural Control and Coordination: key facts
- Organisation of the neural system
- Autonomic = sympathetic + parasympathetic.
- Sodium-potassium pump
- Keeps the outside positive and inside negative at rest.
- Impulse events
- Action potential = reversed polarity at the stimulated site.
- Chemical synapse
- New potential: excitatory or inhibitory.
- Brain parts
- Brain stem = midbrain + pons + medulla.
- Meninges (outside to inside)
- Pia mater touches brain tissue.
Neural Control and Coordination: diagrams to practise
Practise each one on paper: draw it from the checklist, then tick off every label.
Structure of a neuron
Draw a labelled diagram of a neuron.
Draw
- A star-shaped cell body with a nucleus and dots (Nissl's granules); several short branched dendrites.
- A long axon with segments of myelin sheath separated by gaps (nodes of Ranvier); a Schwann cell nucleus on one segment.
- Branched axon terminals ending in swollen synaptic knobs.
Label
- Dendrites
- Cell body
- Nucleus
- Nissl's granules
- Axon
- Myelin sheath
- Schwann cell
- Node of Ranvier
- Axon terminal
- Synaptic knob
Watch out: Draw an arrow showing the direction of the impulse: dendrite → cell body → axon.
Axon terminal and chemical synapse
Draw a diagram showing an axon terminal and a synapse.
Draw
- A rounded synaptic knob with several small circles (vesicles) near its lower membrane.
- A narrow gap below it (synaptic cleft), then the post-synaptic membrane with receptor shapes.
- Dots (neurotransmitter) being released into the cleft and binding to receptors.
Label
- Axon terminal
- Synaptic vesicles
- Neurotransmitters
- Pre-synaptic membrane
- Synaptic cleft
- Receptors
- Post-synaptic membrane
Watch out: Show an arrow for the direction of transmission (pre to post).
Sagittal section of the human brain
Draw a labelled diagram of the human brain (sagittal section).
Draw
- A large folded cerebrum occupying most of the outline, with a curved band (corpus callosum) beneath it.
- Thalamus below the corpus callosum and hypothalamus below the thalamus with the pituitary hanging beneath.
- Small midbrain region, then pons, medulla continuing into the spinal cord; folded cerebellum behind the pons.
Label
- Cerebrum
- Cerebral cortex
- Corpus callosum
- Thalamus
- Hypothalamus
- Midbrain
- Pons
- Cerebellum
- Medulla oblongata
- Spinal cord
Watch out: Shade the cerebellum with fine folds; place it behind and below the cerebrum.
How the school exam asks Neural Control and Coordination
The question patterns to expect, and the method that works for each.
| Question type | How it is asked | Method |
|---|---|---|
| One-liners (1 mark) | Nodes of Ranvier, Nissl's granules, corpus callosum, corpora quadrigemina, location of bipolar neurons, function of medulla. | Name and location or function in one line. |
| Comparisons (2-3 marks) | CNS vs PNS; myelinated vs non-myelinated; dendrite vs axon; electrical vs chemical synapse; thalamus vs hypothalamus; resting vs action potential. | Matched points in a table. |
| Process (3-5 marks) | Polarisation, depolarisation and conduction; transmission across a chemical synapse. | Steps in order, naming ions and their direction, charges inside and outside. |
| Diagrams (3-5 marks) | Structure of a neuron; sagittal section of the brain; axon terminal and synapse. | Label 6-8 parts; show synaptic knob, vesicles and cleft clearly. |
| Application (2-3 marks) | Effect of damage to a brain region, blocking the Na⁺-K⁺ pump or Na⁺ channels, drugs at synapses. | Identify the region or step affected, then predict the effect. |
Tricks to remember Neural Control and Coordination
Short memory aids. Say each one aloud once, then use it on a question the same day.
DAP: Dura, Arachnoid, Pia
From outside in: Don't Ask Please. Pia is 'pious' and hugs the brain.
Use it when: Order of meninges.
Multi in the cortex, Bi in the eye, Uni in the embryo
Multipolar (cerebral cortex), bipolar (retina), unipolar (embryonic stage).
Use it when: Neuron types and locations.
Salt in, Potassium out
Depolarisation: Na⁺ rushes in; repolarisation: K⁺ moves out. Pump: '3 out, 2 in'.
Use it when: Ion movements.
Thalamus relays, Hypothalamus regulates
Thalamus = sensory and motor relay; hypothalamus = temperature, hunger, thirst, hormones.
Use it when: Thalamus vs hypothalamus.
Pons = Bridge
Pons (Latin 'bridge') links brain regions by fibre tracts; medulla runs vital reflexes; cerebellum balances.
Use it when: Hindbrain functions.
Brain stem = M + P + M
Midbrain + Pons + Medulla.
Use it when: Brain stem composition.
Neural Control and Coordination: exam-level solved questions
Ordered from exam level to HOTS. Cover the solution, write your own, then compare step by step.
Example 1: Bipolar neurons · 1 mark · MCQExam level
Bipolar neurons are found in the:
(a) cerebral cortex (b) retina (c) spinal cord (d) embryo only
Try it first, then show the solutionSolution
- Bipolar neurons (one axon, one dendrite) occur in the retina.
Answer: (b) retina
Example 2: Electrical synapse speed · 1 mark · Assertion-reasonExam level
Assertion (A): Impulse transmission across an electrical synapse is faster than across a chemical synapse.
Reason (R): At electrical synapses current flows directly between the closely placed neurons.
(a) Both A and R are true and R is the correct explanation of A.
(b) Both A and R are true but R is not the correct explanation of A.
(c) A is true but R is false.
(d) A is false but R is true.
Try it first, then show the solutionSolution
- No chemical step is needed, so it is faster; R explains A.
Answer: (a)
Example 3: Hypothalamus · 2 marks · Very short answerExam level
State the location and two functions of the hypothalamus. (2 marks)
Try it first, then show the solutionSolution
- At the base of the thalamus in the forebrain. (1)
- Controls body temperature and urge for eating and drinking; secretes hypothalamic hormones via neurosecretory cells (any two). (1)
Answer: Base of thalamus; temperature, hunger/thirst, hormones.
Example 4: Ion pump arithmetic (solved two ways) · 2 marks · Very short answerHarder exam level
A neuron's Na⁺-K⁺ pumps move 6000 Na⁺ ions out of the cell in a given time. How many K⁺ ions do they bring in, and how many pump cycles occurred? (2 marks)
Try it first, then show the solutionSolution
- Method 1 (cycles first): each cycle moves 3 Na⁺ out, so cycles = 6000 ÷ 3 = 2000; K⁺ in = 2 × 2000 = 4000. (1)
- Method 2 (ratio): Na⁺ : K⁺ = 3 : 2, so K⁺ = 6000 × 2/3 = 4000; cycles = 4000 ÷ 2 = 2000. (1)
Answer: 4000 K⁺ in; 2000 cycles.
Example 5: Conduction along an axon · 3 marks · Short answerHarder exam level
Explain how an action potential generated at point A spreads to point B on the axon. (3 marks)
Try it first, then show the solutionSolution
- At A, Na⁺ entry has reversed polarity: inside positive, outside negative; at B, the membrane is still positive outside, negative inside. (1)
- Current flows on the inner surface from A to B and on the outer surface from B to A, completing a local circuit. (1)
- This reverses polarity at B, generating an action potential there; meanwhile K⁺ outflow restores A, so the impulse moves forward. (1)
Answer: Local currents depolarise the next point; the wave travels along.
Example 6: Direction of the impulse · 3 marks · Short answerHarder exam level
In a student's diagram of two connected neurons, an arrow runs from the synaptic knob of the second neuron back to the dendrites of the first. Identify the error, state the correct direction of an impulse within a neuron and across a chemical synapse, and explain why it cannot go the other way. (3 marks)
Try it first, then show the solutionSolution
- Within a neuron the impulse runs dendrites → cell body → axon → axon terminals and synaptic knobs. (1)
- Across a chemical synapse it passes only from the pre-synaptic knob to the post-synaptic membrane of the next neuron, so the arrow is reversed. (1)
- Neurotransmitters are stored in synaptic vesicles of the pre-synaptic knob, and their receptors lie only on the post-synaptic membrane, so transmission is one-way. (1)
Answer: The arrow is reversed: dendrite → cell body → axon → knob, then pre- to post-synaptic only, because transmitters are released on one side and received on the other.
Example 7: Synapse-blocking drug · 3 marks · Short answerHOTS / competency
Suppose a drug blocks the receptors on the post-synaptic membrane at excitatory chemical synapses. Predict the effect on impulse transmission and explain why the pre-synaptic neuron still releases neurotransmitter. (3 marks)
Try it first, then show the solutionSolution
- The impulse still reaches the axon terminal and causes vesicles to fuse and release neurotransmitter, because these steps occur in the pre-synaptic neuron. (1)
- But the neurotransmitter cannot bind blocked receptors, so ion channels on the post-synaptic membrane do not open. (1)
- No new potential forms in the post-synaptic neuron, so transmission stops at that synapse (e.g. muscles controlled by it would not respond). (1)
Answer: Release continues, but no post-synaptic potential; transmission is blocked.
Example 8: Pump poison · 3 marks · Short answerHOTS / competency
A poison stops the Na⁺-K⁺ pump but does not block ion channels. Predict what happens to the neuron's ability to fire repeatedly over time, and explain. (3 marks)
Try it first, then show the solutionSolution
- The pump maintains high K⁺ inside and high Na⁺ outside (the concentration gradients). (1)
- Each action potential lets some Na⁺ in and K⁺ out; without the pump, these gradients slowly run down. (1)
- The resting potential gradually disappears and the membrane can no longer be depolarised effectively, so the neuron stops firing; a few impulses may still occur at first. (1)
Answer: Gradients run down; firing fails after a while.
Case-study practice (Section E style)
Read the situation, then answer every part. In a school exam set on the board pattern this is a 4-mark question split into 1 + 1 + 2 marks.
Stroke patient
Suppose an elderly man suffers a stroke affecting part of his left cerebral hemisphere. He cannot move his right arm properly and has trouble speaking and remembering words, but his breathing and heartbeat are normal.
(i) · 1 mark
Which part of the brain is affected: forebrain, midbrain or hindbrain?
Answer
Answer: Forebrain (cerebrum).
Cerebral hemispheres are in the forebrain.
(ii) · 1 mark
Which areas of the cortex are likely damaged, given his symptoms?
Answer
Answer: Motor and association areas.
Movement uses motor areas; memory and communication use association areas.
(iii) · 2 marks
Why are breathing and heartbeat normal? Name the region controlling them.
Answer
Answer: The medulla oblongata in the hindbrain is undamaged.
Centres for respiration and cardiovascular reflexes are in the medulla (1), which lies in the hindbrain/brain stem, away from the damaged cerebrum (1).
Recording a nerve impulse
Imagine a student watches a lab demonstration where electrodes record the charge inside an axon. At rest the inside is negative. After a stimulus, the inside briefly becomes positive and then returns to negative within a few thousandths of a second.
(i) · 1 mark
What is the negative resting value called?
Answer
Answer: Resting potential.
Potential difference across a resting (polarised) membrane.
(ii) · 1 mark
Which ion movement makes the inside positive?
Answer
Answer: Na⁺ rushing in.
The membrane becomes freely permeable to Na⁺.
(iii) · 2 marks
Explain why the inside returns to negative and how the gradients are restored over time.
Answer
Answer: K⁺ moves out; the Na⁺-K⁺ pump restores gradients.
The Na⁺ permeability rise is short-lived and is followed by increased K⁺ permeability; K⁺ diffuses out, restoring the negative inside (1). The pump moves 3 Na⁺ out and 2 K⁺ in using ATP, maintaining the concentration gradients (1).
Where the marks are
How a typical answer is split into step marks. Show every step: a right final answer alone rarely earns full marks.
Fibre P is taken from a cranial nerve and fibre Q from the autonomic neural system. Which is more likely to be myelinated, and what would you see along P that is missing in Q? (2 marks) (2 marks)
| Step | Marks |
|---|---|
| P is likely myelinated (myelinated fibres occur in spinal and cranial nerves); Q is likely non-myelinated (common in the autonomous and somatic neural systems). | 1 |
| Along P, Schwann cells form a myelin sheath interrupted by gaps, the nodes of Ranvier; in Q a Schwann cell surrounds the axon but wraps no myelin around it. | 1 |
K⁺ is far more concentrated inside a resting axon than outside, yet the inner surface is negative. Explain why, giving three features of the resting membrane. (3 marks) (3 marks)
| Step | Marks |
|---|---|
| The membrane is impermeable to the negatively charged proteins of the axoplasm, so these negative charges stay inside. | 1 |
| The Na⁺-K⁺ pump moves 3 Na⁺ out for every 2 K⁺ in, a net outward movement of positive charge, and the membrane is nearly impermeable to Na⁺, so it cannot leak back in. | 1 |
| The membrane is comparatively more permeable to K⁺, which can move outwards down its gradient; together these leave the outer surface positive and the inner surface negative (the resting potential). | 1 |
Five patients each have damage to one part of the forebrain. Name the part in each case and its position: (a) cannot regulate body temperature or feel thirst normally; (b) shows changed emotional reactions and motivation; (c) sensory and motor signals are poorly coordinated; (d) the two cerebral hemispheres cannot share information; (e) memory and communication are impaired though sensation is normal. (5 marks) (5 marks)
| Step | Marks |
|---|---|
| (a) Hypothalamus, at the base of the thalamus; it has centres for body temperature and the urge to eat and drink. | 1 |
| (b) Limbic system (amygdala, hippocampus) in the inner parts of the cerebral hemispheres, working with the hypothalamus. | 1 |
| (c) Thalamus, around which the cerebrum wraps; the major coordinating centre for sensory and motor signalling. | 1 |
| (d) Corpus callosum, the tract of nerve fibres connecting the left and right cerebral hemispheres. | 1 |
| (e) Association areas of the cerebral cortex (grey matter), responsible for intersensory associations, memory and communication. | 1 |
Where students lose marks in Neural Control and Coordination
The slips examiners see most often, and what to write instead.
Mistake: Saying the inside of a resting axon is positive
Mixing resting and action potentials.
Do this: At rest: outside positive, inside negative. During the action potential: reversed.
Usually costs: 1 mark.
Mistake: Writing that K⁺ rushes in to cause depolarisation
Ions swapped.
Do this: Na⁺ rushes in to depolarise; K⁺ moves out to repolarise.
Usually costs: 1 mark.
Mistake: Writing that the pump moves 2 Na⁺ out and 3 K⁺ in
Numbers reversed.
Do this: 3 Na⁺ out for every 2 K⁺ in.
Usually costs: ½-1 mark.
Mistake: Placing the medulla in the midbrain or forebrain
Brain parts not organised.
Do this: Medulla is in the hindbrain with pons and cerebellum.
Usually costs: ½ mark.
Mistake: Writing about reflex arc or eye and ear in detail
Older editions included them.
Do this: These are not in the 2026-27 syllabus; focus on neuron, impulse, synapse and brain.
Usually costs: Time lost.
Mistake: Saying electrical synapses are the common type
Electrical sounds natural for nerves.
Do this: Electrical synapses are rare; chemical synapses are common.
Usually costs: ½ mark.
NCERT exercise guide: Neural Control and Coordination
What each exercise in the NCERT chapter tests, how to approach it, and a question of the same kind solved step by step. Questions here are written in our own words.
Exercises on brain structure and the neural system
What it tests: Structure of the brain, CNS vs PNS, short notes on forebrain, midbrain, hindbrain, thalamus vs hypothalamus, diagrams of neuron and brain.
How to approach it: Organise by forebrain/midbrain/hindbrain with parts and functions; use comparison tables.
Brain injury (own question)
A patient's brain scan shows damage to the medulla. Which body functions might be affected?
Show the solutionSolution
- The medulla contains centres for respiration, cardiovascular reflexes and gastric secretions.
- Damage could disturb breathing, heart rate/blood pressure control and stomach secretions.
Answer: Breathing, heart reflexes and gastric secretion.
Exercises on nerve impulse and synapse
What it tests: Polarisation, depolarisation, resting vs action potential, chemical synapse, role of Na⁺, myelinated vs non-myelinated axons, dendrites vs axons.
How to approach it: State ion permeabilities and directions; list synaptic steps in order.
Pump numerical (own question)
If a Na⁺-K⁺ pump completes 100 cycles, how many Na⁺ and K⁺ ions does it move, and what is the net charge moved out?
Show the solutionSolution
- Na⁺ out = 3 × 100 = 300; K⁺ in = 2 × 100 = 200.
- Net positive charge moved out = 300 − 200 = 100 (one per cycle). Check: each cycle moves 3 out, 2 in, net 1 out; × 100 = 100.
Answer: 300 Na⁺ out, 200 K⁺ in; net 100 positive charges out.
Practice questions on Neural Control and Coordination
Write each answer on paper first. Open the hint only if you are stuck, and the answer only when you have finished.
Q1 · 1 mark · MCQExam level
The innermost layer of the cranial meninges is the:
(a) dura mater (b) arachnoid (c) pia mater (d) corpus callosumHint
In contact with brain tissue.
Answer
(c) pia mater
Q2 · 1 mark · MCQExam level
Corpora quadrigemina are found in the:
(a) forebrain (b) midbrain (c) pons (d) medullaHint
Four dorsal swellings.
Answer
(b) midbrain
Q3 · 2 marks · Very short answerExam level
Name the three types of neurons by structure and give where each is found. (2 marks)
Hint
Multi, bi, uni.
Answer
Multipolar: cerebral cortex; bipolar: retina (1). Unipolar: embryonic stage (1).
Q4 · 2 marks · Very short answerHarder exam level
What is the role of the sympathetic and parasympathetic neural systems? (2 marks)
Hint
Divisions of autonomic system.
Answer
They are the two divisions of the autonomic system carrying impulses from the CNS to involuntary organs and smooth muscles (1); they usually have opposite effects, e.g. sympathetic increases and parasympathetic decreases heart rate (1).
Q5 · 2 marks · Very short answerHarder exam level
Why are neurons called excitable cells? (2 marks)
Hint
Polarised membrane.
Answer
Their membranes are in a polarised state with ion channels that are selectively permeable to different ions (1); a stimulus can change permeability and generate an action potential (1).
Q6 · 2 marks · Very short answerHarder exam level
State the functions of the pons, cerebellum and medulla. (2 marks)
Hint
Hindbrain.
Answer
Pons: fibre tracts interconnecting brain regions; cerebellum: highly folded with many neurons, coordinating movement and balance (1). Medulla: centres for respiration, cardiovascular reflexes and gastric secretions (1).
Q7 · 3 marks · Short answerHarder exam level
At a chemical synapse, predict and explain the result if (a) the synaptic vesicles cannot fuse with the pre-synaptic membrane, and (b) the neurotransmitter opens channels whose ions make the post-synaptic neuron harder to excite. (c) What is the fluid-filled gap called? (3 marks)
Hint
Release, binding, new potential.
Answer
(a) No neurotransmitter is released into the synaptic cleft, so nothing binds the post-synaptic receptors and the impulse stops at the synaptic knob (1). (b) The new potential generated is inhibitory rather than excitatory, so the post-synaptic neuron becomes less likely to fire (1). (c) The synaptic cleft (1).
Q8 · 3 marks · Short answerHarder exam level
Explain the functions of the cerebral cortex areas and of the limbic system. (3 marks)
Hint
Motor, sensory, association; emotions.
Answer
Motor areas control movements; sensory areas receive sensations (1). Association areas handle intersensory associations, memory and communication (1). Limbic system (amygdala, hippocampus) with hypothalamus regulates sexual behaviour, emotions such as excitement, pleasure, rage and fear, and motivation (1).
Q9 · 5 marks · Long answerHarder exam level
(a) Describe the structure of a neuron, including the difference between myelinated and non-myelinated axons. (b) Why does a neuron keep using ATP even when it is not conducting impulses, and what would happen if it could not? (5 marks)
Hint
Cell body, dendrites, axon, Schwann cells; the pump is active transport.
Answer
(a) Cell body with cytoplasm, organelles and Nissl's granules; short branched dendrites with Nissl's granules carry impulses towards the cell body; a long axon carries impulses away and ends in branches with synaptic knobs holding vesicles of neurotransmitters (2). Myelinated axons are wrapped by a myelin sheath from Schwann cells, with gaps called nodes of Ranvier (spinal and cranial nerves); in non-myelinated axons a Schwann cell surrounds the axon without forming myelin (1). (b) The Na⁺-K⁺ pump is active transport: it uses ATP to move 3 Na⁺ out and 2 K⁺ in, keeping the concentration gradients that make the resting membrane polarised (1). Without ATP the gradients would gradually run down, the resting potential would disappear and the neuron could not generate action potentials (1).
Q10 · 3 marks · Short answerHOTS / competency
Suppose a disease destroys the myelin sheath of some nerve fibres. Predict the effect on nerve impulses and on the person's movements, and explain. (3 marks)
Hint
Insulation and nodes.
Answer
Myelin insulates axons so that impulses travel quickly from node to node of Ranvier (1). Without myelin, impulses become slow or may fail to pass, as current leaks across the bare membrane (1). Signals from the CNS to muscles (and sensory signals back) are delayed or lost, causing weakness, poor coordination or numbness (1).
Q11 · 3 marks · Short answerHOTS / competency
A person cannot feel hunger normally and has trouble controlling body temperature, but thinking and memory are unaffected. Predict which brain structure is damaged and justify, ruling out the cerebrum. (3 marks)
Hint
Base of thalamus.
Answer
The hypothalamus (1). It has centres controlling body temperature and the urge for eating and drinking (1). Thinking and memory depend on cerebral cortex association areas, which are working normally, so the cerebrum is not the damaged part (1).
Q12 · 1 mark · Assertion-reasonHOTS / competency
Assertion (A): The outer surface of a resting axon is positively charged.
Reason (R): The Na⁺-K⁺ pump moves three Na⁺ out for every two K⁺ it moves in.
(a) Both A and R are true and R is the correct explanation of A.
(b) Both A and R are true but R is not the correct explanation of A.
(c) A is true but R is false.
(d) A is false but R is true.Hint
Net positive charge moved out.
Answer
(a)
Test your recall
Answer in your head or on paper first, then open the card. Pulling an answer out of memory makes it stick far better than re-reading.
1.What kind of neural system does Hydra have?Show answer
A network of neurons.
2.Which fibres carry impulses from organs to the CNS?Show answer
Afferent fibres.
3.What are Nissl's granules?Show answer
Granular bodies in the cell body and dendrites of neurons.
4.Which cells form the myelin sheath?Show answer
Schwann cells.
5.What are nodes of Ranvier?Show answer
Gaps between adjacent myelin sheaths on an axon.
6.Where are myelinated fibres found?Show answer
In spinal and cranial nerves.
7.What does the synaptic knob contain?Show answer
Synaptic vesicles with neurotransmitters.
8.What is the gap at a chemical synapse called?Show answer
Synaptic cleft.
9.Which structure connects the two cerebral hemispheres?Show answer
Corpus callosum.
10.Name two structures of the limbic system.Show answer
Amygdala and hippocampus.
11.Which canal passes through the midbrain?Show answer
The cerebral aqueduct.
12.Why is the cerebellum's surface highly folded?Show answer
To provide extra space for many more neurons.
Best order to study it
- Learn what coordination means and how neural systems differ across animals.
- Learn the divisions of the human neural system: CNS, PNS, somatic, autonomic, visceral.
- Learn neuron structure and types with a labelled diagram.
- Learn resting potential, depolarisation and conduction step by step.
- Learn electrical and chemical synapses and the steps of chemical transmission.
- Learn the meninges and the parts of the forebrain, midbrain and hindbrain with functions and a brain diagram.
Quick revision checklist
The night before the exam: can you do each of these without looking?
- Can you define coordination and give an example during exercise?
- Can you draw the divisions of the human neural system as a tree?
- Can you draw a neuron and label dendrites, cell body, axon, myelin sheath, nodes of Ranvier and synaptic knob?
- Can you explain why the resting membrane is polarised?
- Can you describe how an action potential is generated and conducted?
- Can you list the steps of transmission at a chemical synapse?
- Can you name the parts of the forebrain and their functions?
- Can you name the parts of the hindbrain and the brain stem?
Neural Control and Coordination: frequently asked questions
How many marks does this chapter carry in Class 11 Biology (2026-27)?
Marks are set by unit. This chapter is in Unit V, Human Physiology, which carries 18 of the 70 theory marks together with the other human physiology chapters.
Are reflex action, the eye and the ear in the syllabus?
No. Reflex action and reflex arc, and sensory reception and processing (eye and ear), were removed. The syllabus covers neurons, nerves, CNS, PNS, visceral nervous system and generation and conduction of nerve impulses.
Why does a myelinated fibre conduct faster than a non-myelinated one?
The myelin sheath insulates the axon, so the impulse effectively jumps from one node of Ranvier to the next instead of travelling continuously along every point of the membrane.
What is the difference between a nerve and a neuron?
A neuron is a single nerve cell. A nerve is a bundle of many nerve fibres (axons) wrapped in connective tissue, part of the PNS.
What does the visceral nervous system do?
It is the part of the PNS made of nerves, fibres, ganglia and plexuses that carry impulses between the CNS and internal organs (viscera) in both directions.
Based on: CBSE Biology (044) syllabus 2026-27 (Classes XI-XII); NCERT Biology, Textbook for Class XI, Chapter 18 (Reprint 2026-27)