CBSE Class 12 Biology 2026: question 33(a)
Set in the CBSE Class 12 board exam of 2026, paper 57/1/1, section E, question 33(a), for 5 marks. Try it first; the hints and our step-by-step solution are below.
Q33(a) · 5 marks · Long answerHuman Health and Disease
Answer the following.
- (i)0 marks
Name the protozoan species that is responsible for causing the most serious and even fatal malarial disease.
- (ii)2 marks
Name the host in which the parasite completes its sexual stages and explain the changes taking place.
- (iii)0 marks
How does the parasite damage the human body after entering the blood stream ?
- (iv)1 mark
Suggest two effective preventive measures to control the spread of this disease in endemic regions.
Source: official question paper from cbse.gov.in (PDF). See it in the full 2026 board paper, set 57/1/1.
Hints
Open one hint at a time and try again before the next.
Hint 1
Recall the life cycle of Plasmodium in two hosts.
Hint 2
Which host takes up gametocytes, and where do the sporozoites end up?
Hint 3
Think of the toxin released when the parasite bursts out of red blood cells.
Step-by-step solution
Each step shows the marks it earns, as an examiner would award them. Checked by an independent re-solve from the question paper.
- ½ mark
(i) Plasmodium falciparum causes malignant malaria, the most serious and often fatal form.
- ½ mark
(ii) Host. The sexual stages are completed in the female Anopheles mosquito.
- 1½ marks
(ii) Changes in the mosquito.
- When the mosquito bites an infected person, it takes up gametocytes along with the blood.
- In the mosquito's gut the gametes form and fuse (fertilisation), and the parasite develops further, producing sporozoites.
- The sporozoites migrate to the mosquito's salivary glands. From there they are injected into a new human host at the next bite.
- 1½ marks
(iii) Sporozoites entering the blood first reach the liver cells and multiply there. They then attack red blood cells and multiply asexually inside them. The RBCs rupture and release a toxic substance, haemozoin. Haemozoin causes chills and high fever that recur every 3–4 days.
- 1 mark
(iv) Any two preventive measures:
- Avoid stagnant water in and around homes, and clean water coolers regularly, so that mosquitoes cannot breed.
- Use mosquito nets and wire mesh on doors and windows.
- Introduce larvivorous fish such as Gambusia into ponds.
- Spray insecticides in ditches and drains.
Answer: (i) Plasmodium falciparum; (ii) female Anopheles mosquito – gametocytes taken up, fertilisation and development in the gut, sporozoites move to the salivary glands; (iii) multiply in liver cells, then in RBCs; RBCs rupture releasing haemozoin, causing chills and recurring high fever; (iv) e.g. remove stagnant water, use mosquito nets / Gambusia fish
Where the marks are
- Names Plasmodium falciparum (½ mark)
- Names the female Anopheles mosquito as host (½ mark)
- Gives three changes in the mosquito: gametocyte uptake, fertilisation and development in the gut, sporozoites to the salivary glands (½ × 3 = 1½ marks)
- Describes liver and RBC multiplication, RBC rupture and haemozoin causing chills and fever (1½ marks)
- Gives any two preventive measures (½ + ½ = 1 mark)
Revise the chapter
- Chapter: Human Health and Disease (notes, formulas, where marks are lost and every past question)
- Topic: Common Diseases in Humans and Malaria
More questions from Human Health and Disease
- 2023 board paper, set 57/5/1, Q26(a) · 3 marks“Plasmodium protozoan needs both a mosquito and a human host for its continuity.” Explain.
- 2026 board paper, set 57/5/1, Q19 · 2 marksName the lymphoid organ that acts as a large reservoir of erythrocytes. Explain its role as a lymphoid organ.
- 2026 board paper, set 57/5/1, Q33(a) · 5 marks(i) Draw the structure of an antibody molecule and label any four of its parts. (ii) Differentiate between act…
The question is transcribed from the official paper; figures are described in words. The solution, hints and chapter tag are ours. Spotted an error? Write tosupport@questionbuddy.in.