CBSE Class 12 Biology sample paper 2026-27: question 8
From the official CBSE sample question paper for 2026-27, section A, question 8, for 1 mark. Try it first; the hints and our step-by-step solution are below.
Q8 · 1 mark · MCQCompetency-basedPrinciples of Inheritance and Variation
Study the given pedigree and identify the disease represented
- (A)Myotonic Dystrophy
- (B)Sickle cell anaemia
- (C)Haemophilia
- (D)Colour blindness
Figure in the paper: Pedigree chart: normal parents (male square, female circle) have five children: normal male, affected male, normal male, normal female (carrier-like, unshaded), affected female (shaded circle), normal male. The normal male and normal female in the second generation... the unshaded female (marries a normal male) has an affected son (shaded square) and two normal daughters. See it in the official paper.
Source: official sample paper from cbseacademic.nic.in (PDF). See it in the full Sample paper 2026-27.
Hints
Open one hint at a time and try again before the next.
Hint 1
Are the parents of the affected children themselves affected?
Hint 2
An affected daughter with a normal father rules out X-linked recessive inheritance.
Step-by-step solution
Each step shows the marks it earns, as an examiner would award them. Checked by an independent re-solve from the question paper.
Unaffected parents have both an affected son and an affected daughter, so the trait is recessive and not sex-linked.
- 1 mark
An autosomal recessive disease is sickle cell anaemia. Myotonic dystrophy is dominant, while haemophilia and colour blindness are X-linked. Option (B).
Answer: (B) Sickle cell anaemia
Where the marks are
- Deduces autosomal recessive inheritance and identifies sickle cell anaemia (1 mark)
Revise the chapter
- Chapter: Principles of Inheritance and Variation (notes, formulas, where marks are lost and every past question)
- Topic: Pedigree Analysis and Mendelian Disorders
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