CBSE Class 12 Biology sample paper 2025-26: question 19
From the official CBSE sample question paper for 2025-26, section B, question 19, for 2 marks. Try it first; the hints and our step-by-step solution are below.
Q19 · 2 marks · Very short answerCompetency-basedHuman Health and Disease
The table below shows a hypothetical blood report of a patient.
| Test description | Observed value | Unit | Reference range |
|---|---|---|---|
| Leucocytes | |||
| Total leucocyte count | 1100 | Per Microliter | 4400-11000 |
| Neutrophils | 31 | % | 55-70 |
| Lymphocytes | 25 | % | 20-40 |
| Basophils | 0.5 | % | 0.5 - 1 |
| Eosinophils | 02 | % | 1-4 |
| Monocytes | 0 | % | 1-8 |
A. Looking at the values suggest which defense mechanism/ immunity is affected and state how this defense mechanism provides immunity.
B. Name the barrier with least count and enumerate its role in providing immunity.
Source: official sample paper from cbseacademic.nic.in (PDF). See it in the full Sample paper 2025-26.
Hints
Open one hint at a time and try again before the next.
Hint 1
Look at which values fall below the reference range: neutrophils and monocytes are phagocytes.
Hint 2
Phagocytic WBCs belong to one of the four barriers of innate immunity.
Step-by-step solution
Each step shows the marks it earns, as an examiner would award them. Checked by an independent re-solve from the question paper.
- 1 mark
A. Total leucocyte count (1100), neutrophils (31%) and monocytes (0%) are all below normal. These are phagocytic cells of the cellular barrier, so innate (non-specific) immunity, present from birth, is affected. Innate immunity gives physical, physiological, cellular and cytokine barriers that stop foreign agents entering the body and destroy microbes.
- 1 mark
B. The cellular barrier cell with the least count is the monocyte (0%). Monocytes, and the macrophages formed from them, phagocytose and destroy microbes, preventing microbial growth.
Answer: A. Innate immunity – barriers prevent entry of and destroy foreign agents. B. Cellular barrier – monocytes (0%), which phagocytose and destroy microbes.
Where the marks are
- Identifies innate (non-specific) immunity and how it works through barriers (1 mark)
- Names monocytes of the cellular barrier and their phagocytic role (1 mark)
Revise the chapter
- Chapter: Human Health and Disease (notes, formulas, where marks are lost and every past question)
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