CBSE Class 12 Biology sample paper 2023-24: question 33(a)
From the official CBSE sample question paper for 2023-24, section E, question 33(a), for 5 marks. Try it first; the hints and our step-by-step solution are below.
Q33(a) · 5 marks · Long answerHuman Health and Disease
Explain the role of Primary and Secondary Lymphoid organs with the help of suitable examples.
Source: official sample paper from cbseacademic.nic.in (PDF). See it in the full Sample paper 2023-24.
Hints
Open one hint at a time and try again before the next.
Hint 1
Sort the organs into two groups: those where lymphocytes are made or mature, and those where they meet antigens.
Hint 2
The primary group has two members, one in bones and one near the heart.
Hint 3
For the secondary group, recall the spleen, lymph nodes, Peyer's patches and the tissue lining the body's tracts.
Step-by-step solution
Each step shows the marks it earns, as an examiner would award them. Checked by an independent re-solve from the question paper.
- ½ mark
Lymphoid organs are organs in which lymphocytes originate and/or mature and proliferate.
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Primary lymphoid organs are the bone marrow and the thymus. In these organs, immature lymphocytes differentiate into antigen-sensitive lymphocytes.
- ½ mark
The bone marrow is the main lymphoid organ. All blood cells, including lymphocytes, are produced here, and B-lymphocytes mature here.
- ½ mark
The thymus is a lobed organ lying near the heart, beneath the breastbone. It provides the micro-environment for maturation of T-lymphocytes. It is large at birth and shrinks with age.
- ½ mark
After maturation, lymphocytes migrate to the secondary lymphoid organs. Examples are the spleen, lymph nodes, tonsils, Peyer's patches of the small intestine and the appendix.
- ½ mark
Secondary lymphoid organs are the sites where lymphocytes interact with antigens. The lymphocytes then proliferate to become effector cells.
- ½ mark
The spleen is a large bean-shaped organ containing mainly lymphocytes and phagocytes. It filters the blood by trapping blood-borne microorganisms, and it also stores a large reservoir of erythrocytes.
- ½ mark
Lymph nodes are small solid structures found at intervals along the lymphatic system. They trap microorganisms and other antigens that enter the lymph and tissue fluid.
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Antigens trapped in lymph nodes activate the lymphocytes present there, which triggers the immune response.
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MALT (mucosa-associated lymphoid tissue) lines the respiratory, digestive and urogenital tracts. It makes up about 50% of the body's lymphoid tissue.
Answer: Primary lymphoid organs (bone marrow, thymus) are where lymphocytes are formed and mature into antigen-sensitive cells. Secondary lymphoid organs (spleen, lymph nodes, tonsils, Peyer's patches, appendix, MALT) are where lymphocytes meet antigens and proliferate into effector cells.
Where the marks are
- Definition of lymphoid organs (0.5 mark)
- Primary organs named with their role in differentiation (0.5 mark)
- Bone marrow role (0.5 mark)
- Thymus location and role (0.5 mark)
- Secondary organs named (0.5 mark)
- Role of secondary organs: antigen interaction and proliferation (0.5 mark)
- Spleen structure and function (0.5 mark)
- Lymph nodes trap antigens (0.5 mark)
- Activation of lymphocytes in lymph nodes (0.5 mark)
- MALT, about 50% of lymphoid tissue (0.5 mark)
Revise the chapter
- Chapter: Human Health and Disease (notes, formulas, where marks are lost and every past question)
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